Description
Product Characteristics:
Aliases: 6330443E10Rik antibody, ATP dependent RNA helicase SUPV3L1, mitochondrial antibody, ATP-dependent RNA helicase SUPV3L1 antibody, EC 3.6.1. antibody, MGC109049 antibody, mitochondrial antibody, OTTHUMP00000019719 antibody, S. Cerevisiae suppressor of var 1 3 like 1 antibody, suppressor of var1 (S.cerevisiae) 3 like 1 antibody, Suppressor of var1 3 like 1 (S. cerevisiae) antibody, Suppressor of var1 3 like 1 (S. cerevisiae)(SUV3) antibody, Suppressor of var1 3 like 1 antibody, Suppressor of var1 3 like protein 1 antibody, Suppressor of var1 3-like protein 1 antibody, SUPV 3 L 1 antibody, SUPV3L1 antibody, SUV 3 antibody, SUV 3 L 1 antibody, SUV3 antibody, SUV3 like protein 1 antibody, SUV3-like protein 1 antibody, SUV3_HUMAN antibody, SUV3L1 antibody
Target Information: Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria\, regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA (By similarity)